摘要
目的观察米非司酮配伍米索前列醇不同用药途径对10～16周妊娠的流产效果。方法将168名妊娠10～16周的健康妇女随机分配给以米非司酮150mg后,83例米索前列醇阴道给药、85例米索前列醇空腹口服终止妊娠。结果2组在流产时间、出血量差异无统计学意义(χ2=0.075,P>0.05),口服米索前列醇比阴道给药的不良反应增加(χ2=11.53,P<0.05)。结论米非司酮配伍米索前列醇2种用药途径对10～16周妊娠的终止是有效安全简便方法,在减少不良反应方面米索前列醇用药途径阴道给药组优于口服组。
Objective To observe the effect of Mifepristone and Misoprostol for abortion of pregnancy of 10-16 weeks through different route of administration. Method 168 cases of pregnancies during 10 - 16 weeks were randomized into two groups after taking Mifepristone 150mg： 83 cases were given Misoprostol through vagina and 85 cases took it orally. Results There was no significant difference in abortion time and blood loss between two groups （ x^2 = 0. 075, P 〉 0. 05）. Cases who took Misoprostol orally had more adverse reaction than those who were given Misoprostol through vagina （ x^2 = 11.53, P 〈 0.05）. Conclusion Mifepristone and Misoprostol are effective, safe and simple for abortion of pregnancy of 10 - 16 weeks. Misoprostol given through vagina has less adverse reaction than taking orally.
出处
《职业卫生与病伤》
2007年第4期272-274,共3页
Occupational Health and Damage
关键词
米非司酮
米索前列醇
终止妊娠
Mifepristone
Misoprostol
Termination of pregnancy
