摘要
目的:观察中西医结合治疗早期糖尿病肾病(DN)的疗效。方法:60例DN患者,随机分为对照组20例,治疗组40例。两组患者给予糖尿病教育,饮食控制及适量运动,并在此基础上根据血糖水平酌情应用胰岛素及血管紧张素转换酶抑制剂(ACEI),治疗组在此治疗基础上给予中药降糖益肾汤治疗。两组患者分别与治疗前后记录TG,TC,HDL,LDL,BUN,Scr,B2-MG,FGB等多项指标。结果:对照组总有效率为60%,治疗组总有效率87.5%,两组患者治疗后疗效比较有显著性差异(P<0.01)。两组患者治疗后TC,TG,LDL,Scr,BUN,B2-MG,FGB指标均有所降低,HDL有所升高,但治疗组治疗后上述指标变化更为显著,与治疗前比较有显著性差异(P<0.05,P<0.01);治疗组治疗后TC,TG,LDL,HDL,BUN,FGB指标变化与对照组治疗后比较有显著性差异(P<0.05,P<0.01)。结论:中西医结合治疗早期DN可获得较好的疗效,降糖益肾汤在改善血脂、血糖代谢、肾功能及尿β-2微球蛋白方面具有重要作用。
Objective：To observe the curative effect of integrated Traditional Chinese and western medicine in treating diabetic nephropathy at early stage. Methods： 60 patients with DN were randomly divided into two groups,20cases in the control group and 4-0 in the treatment group. Both the two groups were given diabetes instruction ,diet control ,as well as moderate exercise. Based on the above treatments, insulin and angiotonin were also used according to level of patients blood sugar. Pre-treatment and post-treatment record of index such as TG,TC, BUN in both groups were recorded. Result：Total effective rate in control group was 60%, with 87.5 % in the treatment group. There were significant differences. After the treatment,TC, TG, BUN, HDL, LDL, BUN, FGB decreased and HDL increased in both groups, but the change Was much significant in treatment group. There was also significant difference between them. Conclusion：Treatment of diabetic nephropathy at early stage by integrated Traditional Chinese and western medicine could get good therapeutic effect. Yishen Jiangtang Decoction play an important part in improving blood fat, blood glucose metabolism,renal function,and urine β-2 microglobulin.
出处
《世界中西医结合杂志》
2007年第7期402-404,共3页
World Journal of Integrated Traditional and Western Medicine
关键词
糖尿病肾病
中西医结合治疗
益肾降糖汤
Diabetic nephropathy
Integrated Traditional Chinese and western medicine
Yishen
Jiang tang Decoction
