摘要
目的:比较尿激酶与低分子肝素治疗急性肺血栓栓塞症的效果。方法:急性肺动脉栓塞患者35例,既往均无心肺疾患,行超声和肺通气/灌注扫描后随机分为2组,15例溶栓(尿激酶)治疗,20例抗凝(低分子肝素)治疗。观察抗凝与溶栓前后的症状、血气指标、心电图、超声心动图、肺通气/灌注扫描的变化。结果:症状、血气指标、超声心动图、肺通气/灌注扫描,溶栓组比抗凝组改善明显(P<0.05)。结论:溶栓比抗凝效果好。
OBJECTIVE： To study the efficacy of Urokinase vs.Low Molecular Weight Heparin in the treatment of acute pulmonary thromboembolism.METHODS：A total of 35 patients with acute pulmonary thromboembolism who had no past history of heart and lung diseases were enrolled and randomly assigned to two groups following ultrasonography and pulmonary ventilation/perfusion scanning： 15 were given thrombolysis therapy with urokinase, and 20 given antieoagulation therapy with low molecular weight heparin.Symptoms, arterial blood gas analysis, electrocardiogram, echocardiogram were compared in two groups before and after treatment.RESULTS： The patients receiving thrombolysis therapy had better improvement in symptoms, arterial blood gas index, echocardiogram and the pulmonary ventilation/perfusion scanning than in those receiving anticoagulation therapy（P 〈 0.05） .CONCLUSION： Thrombolysis is more effective than pure anticoagulation for acute pulmonary thromboembolism.
出处
《中国药房》
CAS
CSCD
北大核心
2007年第35期2759-2761,共3页
China Pharmacy
基金
河北省2005年医学科学研究重点课题(05452)
关键词
尿激酶
低分子肝素
急性肺栓塞
溶栓
抗凝
Urokinase
Low molecular weight heparin
Acute pulmonary thromboembolism
Thrombolysis
Anticoagulation
