摘要
目的对桑叶(MorusalbaL.)的活性部位进行化学成分研究。方法用色谱法分离,用波谱法对化合物结构进行鉴定。结果与结论从桑叶活性部位中分出10个化合物,其结构分别为:1-脱氧野尻霉素(1-de-oxynojirimycin,1)、fagomine(2)、1,4-二脱氧-1,4-亚氨基-D-阿拉伯醇(1,4-deoxy-1,4-imino-D-arabinitol,3)、精氨酸醋酸盐(arginineacetate,4)、槲皮素-3-O-β-D-吡喃葡萄糖苷(quercetin3-O-β-D-glucopyranoside,5)、芦丁(rutin,6)、咖啡酸乙酯(caffeicacidethylester,7)、山柰酚-3-O-β-D-吡喃葡萄糖苷(kaempferol-3-O-β-D-glucopy-ranoside,8)、山柰酚-3-O-(6″-O-α-L-鼠李糖基)-β-D-吡喃葡萄糖苷[kaempferol-3-O-(6″-O-α-L-rhamnosyl)-β-D-glucopyranoside,9]、槲皮素(quercetin,10)。桑叶活性部位化学成分主要为生物碱和黄酮类,其中化合物7为首次从该属植物中分得。
AimTo study the constituents of active part from Morus alba L. Methods Ten compounds were isolated by chromatography, and their structures were identified by spectral analyses and chemical evienees.Results rand conclusion The 10 compounds were obtained and identified as 1-deoxynojirimycin（1）, fagomine（ 2 ）, 1, 4-deoxy-1, 4-imino-D-arabinitol （ 3 ）, arginine acetate （4）, quereetin 3-O-β-D-glucopyranoside（S ）, rutin （ 6 ）, caffeic acid ethylester （ 7 ）, kaemDferol-3- O-β-D-ulucopyranoside （ 8 ）. kaempferol-3-O（6＂-O-α-L-rhamnosyl）-β-D-glucopyranoside（9）, and quercetin （10）. The constituents of active part from Morus alba L. mainly are alkaloids and flavonoids , and compound 7 was obtained for the first time from Morus species.
出处
《中国药物化学杂志》
CAS
CSCD
2007年第6期386-389,共4页
Chinese Journal of Medicinal Chemistry
关键词
分离
鉴定
桑叶
降血糖
化学成分
separation
identification
Morus alba L.
lower blood sugars
chemical constituents
