摘要
目的：观察重组组织型纤溶酶原激活剂（ｒｔＰＡ）的临床应用效果，摸索其治疗规律。方法：对８例下肢深静脉血栓形成患者进行静脉溶栓治疗。经患肢静脉给予ｒｔＰＡ总量５０～１００ｍｇ，以治疗前后症状、体征、数字减影血管造影（ＤＳＡ）或血管多普勒彩超评价治疗效果。结果：８例患者症状、体征均获缓解，ＤＳＡ或血管多普勒彩超示血栓形成相关血管再通。结论：ｒｔＰＡ是一种安全、有效的溶栓药物。
Objective:To evaluate the efficacy of the recombinant tissue type plasminogen activator (rt PA)in the treatment of deep vein thrombosis of the lower limbs.Methods:8 patients with deep vein thrombosis of the lower limbs were treated by rt PA with 50 100 mg iv infusion. Effects were evaluated by the symptoms, signs,digital subtraction angiography(DSA)and vascular Doppler ultrasonography around the treatment .Results:Severe clinical symptoms of all patients were relieved. DSA and vascular Doppler ultrasonography indicated the re open of the thrombosis related vessel. Conclusion:The rt PA is an effective and safe thrombolytic agent.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
1997年第2期135-137,共3页
Academic Journal of Second Military Medical University
关键词
下肢静脉
血栓形成
溶栓疗法
RT-PA
thrombosis
thrombolytic therapy
plasminogen activator,recombinant tissue type
