摘要
目的探讨颅颈交界区骨性畸形(CVJBA)术后严重呼吸道并发症(SRTC)的临床特征和治疗。方法1994年1月～2006年12月,我科治疗CVJBA 182例,其中15例术后发生SRTC,回顾性分析有关的临床资料,并以未发生SRTC的167例病人作为对照组。结果治愈9例,3例死于呼吸骤停,3例死于SRTC合并其他并发症。SRTC的发生率为8.2%,病死率为40.0%。术前Karnofsky行为能力评分(KPS)(58.0±10.1)低于对照组(67.0±11.1)(P=0.003)。SRTC与病人的性别、年龄、病程长短、是否合并Chiari畸形和(或)脊髓空洞、手术方式、是否同时气管切开无相关性。结论病情严重的病人发生SRTC的可能性较大。CVJBA术后SRTC可导致病人死亡。及早行气管插管或气管切开呼吸机辅助治疗是提高SRTC疗效的关键。
Objective To study the clinical characteristics and treatment of severe respiratory tract complications （SRTC） after surgery for craniocervical junction bony abnormalities （CVJBA）. Methods The clinical data of 15 patients with postoperative SRTC out of 182 CVJBA patients treated in our department from January 1994 to December 2006 were analyzed retrospectively. The other 167 patients without SRTC served as the control group. Results Nine patients with SRTC were cured, 3 died of apnoea and 3 died of SRTC combined with other complications. The incidence and fatality rate of SRTC were 8.2% and 40% respectively. The preoperative Karnofsky performance score （KPS） of the SRTC group （58.0 ± 10.1） was lower than that of control group （67.0 ± 11.1） （P = 0.003）. There was no correlation between SRTC and gender, age, duration of disease, combined with Chiari malformation and （or） syringomyelia, operative method, simultaneous tracheotomy respectively. Conclusion Postoperative SRTC of severe CVJBA is common, and may be fatal. Early tracheal intubation or tracheotomy and using breathing machine are key points for improving the outcome of SRTC.
出处
《中国微侵袭神经外科杂志》
CAS
2007年第12期539-541,共3页
Chinese Journal of Minimally Invasive Neurosurgery
关键词
颅颈交界区畸形
手术后并发症
呼吸道疾病
craniovertebraljunction abnormalities
postoperative complications
respiratory tract diseases
