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麻杏止咳糖浆微生物限度检查方法的验证

Validation of microbiological test for Maxing cough syrup
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摘要 目的建立麻杏止咳糖浆微生物限度检查法。方法取本品10 mL,加入pH 7.0氯化钠-蛋白胨缓冲液至100 mL中,混匀制成1∶10供试液。结果麻杏止咳糖浆微生物限度验证均能达到药典要求。结论此方法简便,验证结果与药典方法一致,麻杏止咳糖浆细菌数测定,毒菌、醇母菌测定均可按中国药典2005年版一部微生物限度项下常规法进行检查。 Objective To establish the microbiological test for Maxing cough syrup. Methods was prepared , and pH 7.0 Nacl - peptone buffer was added to 100 mL, abtaining 1 : 10 test solution- Results Maxing syrup microbiological test met the pharmacopoeia requirements. Conclusion This method is simple, and the test results were consistent with those obtained by standard method. The determination of Maxing syrup bacteria, fungus, and yeast bacteria can be detected by conventional microbiological limit for the examination in the 2005 edition of the "Chinese Pharmacopoeia" (A).
作者 潘萍 刘岚
出处 《中南药学》 CAS 2007年第6期529-531,共3页 Central South Pharmacy
关键词 麻杏止咳糖浆 微生物限度检查法 验证 Maxing cough syrup microbiological test validation
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