Detection of micrometastases in sentinel lymph node of breast cancer 被引量：1

乳腺癌前哨淋巴结微小转移的检测(英文)

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摘要 Objective： To study the best examination method of micrometastases in sentinel lymph node （SLN） of breast cancer and study the related factors with micrometastases. Methods： By step serial sectioning technique and immunohistochemistry, 121 SLNs and 44 tumors of 59 cases were examined. Results： Micrometastases was found in 17 SLNs （14%） of 14 （24%） cases. The more sections or examination methods, the more micrometastases were found. Micrometastases was related with the tumor size and the expression of c-erbB2, MMP-2 and VEGF. Conclusion： The best examination method is making sections at two levels with 100 pm interval and combination of HE staining and mucl immunohistochemistry. We can get the excellent detection/cost by this method. Micrometastases is a bad prognostic factor.

作者 Tao Zhang Baoning Zhang Baoping Chen Xiliang Wei Hongtu Zhang Yuntian Sun

机构地区 Department of Oncology Surgery Department of Abdomen Surgery Department of Pathology

出处《The Chinese-German Journal of Clinical Oncology》 CAS 2007年第6期562-565,共4页 中德临床肿瘤学杂志（英文版）

关键词 breast cancer sentinel lymph node MICROMETASTASES 淋巴结乳癌治疗方法癌细胞

分类号 R737.9 [医药卫生—肿瘤]

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