摘要
[目的]调查晚期妊娠妇女甲状腺功能减退(甲减)的发生率并分析其对妊娠和胎儿的影响。[方法]对住院分娩孕妇4 639例进行甲状腺功能(甲功)检测,根据甲功检查结果分临床甲减组、亚临床甲减组及正常对照组,分别统计不良妊娠的发生率,并按季度比较高TSH发生率。[结果]4 639例孕妇共检出TSH升高者517例,占11.1%,其中:临床甲减检出率为4.2%(196/46 39),亚临床甲减检出率为6.9%(321/4 639);临床甲减组早产、妊娠高血压疾病、贫血、胎窘、低出生体重发生率均高于正常对照组(P﹤0.05);亚临床甲减组其妊娠高血压疾病、贫血、胎窘的发生率亦高于正常对照组(P﹤0.05);高TSH发生率4个季度之间差异有统计学意义(P﹤0.01)。[结论]孕妇甲减与不良妊娠结局具有相关性,且并发症的发生率与甲减的程度有关。有必要在妊娠期筛查甲功,并建立相应的正常值标准,对甲减及亚临床甲减进行积极诊治。
[Objective] To investigate the incidence of hypothyroidism of late pregnant women and analyze it＇s effects on pregnancy and fetus. [Methods] The thyroid functions of 4 639 pregnant women before delivery were examined. According to the examining results, the inpatients were classified the clinical hypothyroidism group, subclinical hypothyroidism group and control group. Their abnormal pregnant rates were counted respectively. According to the quarter, we compared the incidences of high-level TSH. [Results] 517 cases in 4 639 pregnant women belonged to high-level TSH, and the rate was 11.1%. The incidence of clinical hypothyroidism and subclinical hypothyroidism was 4.2% （196/4 639） and 6.9% （321/4 639）. The incidences of premature delivery, hypertensive disorder complicating pregnancy, anemia, fetal distress and low birth weight in clinical hypothyroidism were higher than those of control group （ P 〈 0.05）. The incidences of hypertensive disorder complicaLing pregnancy, anemia, fetal distress m subclinical hypothyroidism were higher than those of control group （P 〈 0.05 ）. The rates of high-level TSH were obviously different in four quarters （P 〈 0.01 ）. [ Conclusion] The hypothyroidism of pregnant women relates to abnormal pregnant outcome, and the incidence of complication has the con＇elation with the degree of hypothyroidism, lt＇ s necessary to screen the hypothyroidism during pregnancy and set up the normal value. These patients with hypothyroidism and subclinical hypothyroidism should be treated actively.
出处
《现代预防医学》
CAS
北大核心
2008年第1期61-62,共2页
Modern Preventive Medicine
