摘要
目的探讨先天性巨结肠症(HD)合并神经节细胞减少(HYP)与术后肠炎发生的相关性。方法对97例在我院行巨结肠根治术的患儿进行随访,随访时间1.5～8年,平均3.4年。分为两组:A组70例,为HD;B组27例,为HD合并HYP。对其排便功能与术后小肠结肠炎(EC)的发生情况进行分析比较。结果A组术后发生肠炎有8例(11.4%),B组发生肠炎有11例(40.7%),两组相比较差异有统计学意义(P<0.005)。按照李正的评分系统,A组排便功能评分为优者比率为85.7%,明显高于B组的62.9%(P<0.05)。A组便秘复发率为2.9%(2/70),B组为14.8%(4/27),但两者之间差异无统计学意义(P>0.05)。结论HD合并HYP患儿术后较HD更易发生小肠结肠炎,完全切除HYP肠管可降低EC的发生率,减轻肠炎发生的程度。
Objective To assess the relationship between the post-operative enterocolitis （EC） and Hirschsprung＇s disease （HD） combined hypoganglionosis （HYP）. Methods Ninety-seven children with Hirschsprunffs disease were followed-up for 3. 4 years （ 1.5 to 8 years）. They were classified into group A （n= 70） with isolated lid and group B （n = 27） with a combination of lid and HYP. Anorectal function was assessed and the incidences of postoperative EC were compared. Results Eight patients（ 11. 4%）from group A and 11 patients（40. 7%）from group B developed postoperative EC. The incidence of postoperative EC in group A was significantly lower than that in group B（P〈0. 005）. The excellent results, as defined by Li＇s score, in group A（85.7% ）was significantly higher than that in group B （P〈0. 05）. Recurrence of constipation group B and group A were 14.8% （4/27） and 2. 8% （2/70） respectively. However, the difference between the two groups was not statistically significant （P〉0. 05）. Conclusions Postoperative EC was associated with HYP, suggesting that HYP may be a predictive marker for EC. Complete resection of HYP segment may minimize the incidence of postoperative EC.
出处
《中华小儿外科杂志》
CSCD
北大核心
2007年第12期627-629,共3页
Chinese Journal of Pediatric Surgery
