期刊文献+

应激性溃疡的发病机制研究进展 被引量:32

New research of pathogenic mechanism of stress ulcer
下载PDF
导出
摘要 应激性溃疡(seress ulcer,Su)是临床危重疾病的严重并发症,在重症监护病房内的发生率达60%,有较高的死亡率。应激性溃疡的发生是多种因素综合作用的结果。本文就近年来国内外文献报道的SU发病机制及其研究现状进行阐述。 Stress ulcer is complications of clinically critical diseases. The morbidity is at least 60% in ICU, and the mortality is also higher. The stress ulcer is a result of many factors. We introduce the pathogenic mechanism and current research of stress ulcer in domestic and overseas literatures at present.
作者 杨君 解建
出处 《中国急救医学》 CAS CSCD 北大核心 2007年第11期1035-1038,共4页 Chinese Journal of Critical Care Medicine
关键词 应激性溃疡 发病机制 防御因素 损伤因素 Stress ulcer Pathogenic mechanism Defense Injury
  • 相关文献

参考文献25

二级参考文献121

  • 1夏钦贵.促甲状腺素释放激素与胃肠道功能[J].生理科学进展,1993,24(2):168-171. 被引量:3
  • 2王志均.对另一类细胞保护命名的建议──耐受性细胞保护[J].生理科学进展,1994,25(4):293-294. 被引量:4
  • 3罗金燕 龚均.胃肠运动与疾病[M].西安:陕西科学技术出版社,1996.336.
  • 4杨红.应激性溃疡发病的中枢机制[J].生理科学进展,1988,19:218-218.
  • 5[2]Ito M, Shichijo K, Nakashima M, Nakayama T,Naito S, Tsuchiya K, Sekine I. Gastric mucosal blood flow in relation to stress-induced hypercontraction in spontaneously hypertensive rats. Jpn J Physiol, 1994, 44: 717~727.
  • 6[3]Kobayashi K, Kashimak K, Higuchi K. The mechanism of gastrointestinal mucosal injury repair. Nippon Rinsho, 1998, 56: 2215~2222.
  • 7[4]Slomiany BL, Piotrowski J, Slomiany A. Role of endothelin-1 and constitutive nitric oxide synthase in gastric mucosal resistance to indomethacin injury: effect of antiulcer agents. Scand J Gastroenterol, 1999, 34: 459~464.
  • 8[6]Fiorucci S, Antonelli E, Santucci L, Morelli O,Miglietti M, Federici B, Mannucci R, Del Soldato P, Morelli A. Gastrointestinal safety of nitric oxide-derived aspirin is related to inhibition of ICE-like cysteine proteases in rats. Gastroenterology, 1999, 116: 1089~1106.
  • 9Guth PH, Aures D, Panlsen G. Topical aspirin plus HC1 gastric lesions in the rat[J]. Gastroenterology, 1979,76(1): 88 --93.
  • 10Lasky MR, Metzler MH, Phillips JO. A prospective study of omeprazole suspension to prevent clinically significant gastrointestinal bleeding from stress ulcers inmechanically ventilated trauma patients[J]. J Trauma, 1998,44(3) : 527 - 533.

共引文献145

同被引文献341

引证文献32

二级引证文献291

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部