摘要
高血糖在危重病患者中非常普遍。血糖持续高水平与危重病病情呈正相关。危重患者出现高血糖主要由激素应激性胰岛素抵抗效应及炎性细胞因子的作用所致。高血糖对机体各组织器官影响是多方面的,是危重患者病情严重程度的显著标志。强化胰岛素治疗控制血糖水平在4.4～6.1 mmoL/L可以降低危重患者的并发症发生率及死亡率,改善预后,降低医疗费用。最佳的血糖调控方案既要能很好地控制血糖,又不造成低血糖发生。高血糖指数作为评估血糖控制指标比较合理,但是强化胰岛素治疗方案的具体实施有很多实际困难。
Hyperglycemia is common in critically ill patients. Continuous high level of blood glucose has a positive correlation with the conditions of critically ill patients. The presence of the hyperglycemia in critically illness patients is mainly induced hy the effects of hormone stress on insulin resistance and the inflammatory eytokine action. Hyperglycemia, which is an important sign showing the conditions of a critically ill patient, has various eli;eels on body tissues. Tight control of blood glucose at a level between 4.4 mmol/L and 6.1 mmol/L by intensive insulin therapy are able to decrease the colnplieation incidence arid mortality of critical illness, improve prognosis, and reduce the expenses for medical eare. The best regulation of blood glucose can not only control the blood glucose at proper level but also avoid the occurrence of hypoglyeemic. It is more resonable to evaluate the control indexes of blood glucose by hyperglycemia index than others, but the implementation of intensive insulin therapy has to face many praclical difficulties.
出处
《中国急救医学》
CAS
CSCD
北大核心
2007年第11期1044-1046,共3页
Chinese Journal of Critical Care Medicine
关键词
危重病
高血糖
胰岛素抵抗
强化胰岛素治疗
高血糖指数
Critical illness
Hyperglycemia
Insulin resistance
Intensive insulin therapy
Hyperglycemic index
