期刊文献+

幽门螺杆菌粪便抗原免疫卡诊断幽门螺杆菌感染的Meta分析 被引量:2

Study on the value of Helicobacter pylori (H. pylori) stool antigen ImmunoCard STAT in the diagnosis of H, pylori infection: a Meta-analysis
原文传递
导出
摘要 目的评价幽门螺杆菌粪便抗原免疫卡诊断幽门螺杆菌感染的精确性。方法计算机检索Medline(1966-2007年4月)、EMbase(1985-2007年4月)和中国期刊全文数据库(1994-2007年)有关幽门螺杆菌粪便抗原免疫卡诊断幽门螺杆菌感染的临床试验,按Cochrane协作网推荐的方法进行Meta分析。结果共11篇文献被纳入评价。合并敏感性和合并特异性分别为0.93(95%CI:0.91-0.94)、0.93(95%CI:0.90-0.95),合并阳性似然比和合并阴性似然比分别为12.01(95%CI:8.90-16.19)、0.08(95%CI:0.07-0.11)。合并诊断优势比为160.14(95%CI:100.43-255.34)。SROC曲线下面积为0.974±0.005。结论幽门螺杆菌粪便抗原免疫卡是一种精确无创的诊断成年人幽门螺杆菌感染方法。 Objective To evaluate the accuracy of the Helicobacter pylori (H. pylori) stool antigen (HpSA) test and ImmunoCard STAT HpSA in the primary diagnosis of H. pylori infection. Methods We searched Medline ( 1966 - 2007.4 ), EMbase ( 1985 - 2007.4 ), Chinese Journals Full-text Database (CJFD) (1994- 2007) etc. to identify Clinical Trials of ImmunoCard STAT HpSA for the primary diagnosis of H. pylori infection. Meta-analysis was conducted using the method recommended by The Cochrane Collaboration Center. Results Eleven trials were included with pooled sensitivity, pooled specificity as 0.93 ( 95 % CI : 0.91- 0.94 ), 0.93 ( 95 % CI : 0.90- 0.95 ), respectively. Pooled positive likelihood ratio and pooled negative likelihood ratio were 12.01 ( 95 % CI : 8.90-16.19 ), 0.08 ( 95 % CI : 0.07-0.11 ), respectively with the pooled diagnostic odds ratio as 160.14 (95 % CI : 100.43-255.34 ). The area under the summary receiver operating characteristic (SROC) was 0. 974±0. 005. Conclusion ImmunoCard STAT HpSA appeared to be an accurate non-invasive method for the initial diagnosis of H. pylori infection.
出处 《中华流行病学杂志》 CAS CSCD 北大核心 2008年第1期71-74,共4页 Chinese Journal of Epidemiology
关键词 幽门螺杆菌 粪便抗原 诊断试验 META分析 Helicobacter pylori Stool antigen Diagnostic test Meta-analysis
  • 相关文献

参考文献9

二级参考文献46

  • 1M Hobsley,Fl Tovey.Helicobacter pylori: the primary cause of duodenal ulceration or a secondary infection?[J].World Journal of Gastroenterology,2001,7(2):149-151. 被引量:13
  • 2王化冰,林三仁,周丽雅,许乐,田自然.幽门螺杆菌粪便抗原试验检测幽门螺杆菌感染的临床评价[J].中华消化杂志,2005,25(1):15-18. 被引量:21
  • 3郭银燕,张澍田,彭晓霞,詹思延.幽门螺杆菌粪便抗原诊断方法的系统评价[J].中华医学杂志,2005,85(22):1564-1567. 被引量:12
  • 4Chang PS, Ni YH, Chang MH. Household Helicobacter pylori antibody survey in children with upper gastrointestinal symptoms. Acta Paediatr Taiwan 2003;44:336-338.
  • 5Coppola N, De Stefano G, Marrocco C, Scarano F, Scolastico C,Tarantino L, Rossi G, Battaglia M, Onofrio M, D'Aniello F, Pisapia R, Sagnelli C, Sagnelli E, Piccinino F, Giorgio A, Filippini P.Helicobacter spp. and liver diseases. Infez Med 2003;4:201-207.
  • 6Abbasciano V, Sartori S, Trevisani L, Girometti R, Ranzini M,Nielsen I, Mazzotta D, Vecchiatti G, Bononi A, Guglielmini C.Comparison of magnesium concentration in serum, erythrocytes and gastric tissue in two groups of patients affected by chronic gastritis, Helicobacter pylori negative and positive.Magnes Res 2003;16:281-286.
  • 7Mittal SK, Mathew JL. Helicobacter pylori infection in children:a review. Trop Gastroenterol 2003;24:106-115.
  • 8Rieder G, Hofmann JA, Hatz RA, Stolte M, Enders GA. Upregulation of inducible nitric oxide synthase in ftelicobacter pylori-associated gastritis may represent an increased risk factor to develop gastric carcinoma of the intestinal type. lnt J Med Microbiol 2003;293:403-412.
  • 9Okuda M, Nakazawa T, Booka M, Miyashiro E, Yosikawa N.Evaluation of a urine antibody test for Helicobacter pylori in Japanese children. J Pediatr 2004;144:196-199.
  • 10Tanaka I, Tatsumi Y, Kodama T, Kato K, Fujita S, Mitsufuji S,Kashima K. Effect of Helicobacter pylori eradication on gastroesophageal function. J Gastroenterol Hepatol 2004;19:251-257.

共引文献113

同被引文献73

引证文献2

二级引证文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部