摘要
目的评价猴头菇胃肠保健口服液对胃黏膜损伤的保护功能。方法建立灌胃酒精致大鼠急性胃黏膜损伤和胃壁注射冰醋酸致大鼠慢性胃溃疡两种模型,连续灌胃30 d,实验结束时测量各实验组胃黏膜损伤面积或体积,检查猴头菇胃肠保健口服液对胃黏膜损伤的保护功能[1]。结果猴头菇胃肠保健口服液对大鼠慢性胃溃疡有明显的保护作用,低剂量组差异非常显著(P<0.01),中、高剂量组差异显著(P<0.05);对大鼠急性胃黏膜损伤无明显的保护作用(P>0.05)。结论猴头菇胃肠保健口服液对大鼠慢性胃溃疡具有保护功能。
Objective To evaluate the protective effect of Houtougu gastrointestinal health oral liquid on gastric mueosal lesion. Methods The experimental acute gastric mueosal injury in rats was established by intragastrie ethanol, and the experimental chronic gastric ulcer in rats was established by injecting acetic acid in the stomach mueosa, orally administered with different dosage samples, measured the area or eubage of mueosal lesion at the end of the experiment. Results In the chronic gastric ulcer model group obvious protective effect was observed in the middle dosage group ( P 〈 0.05 ) ,the high dosage group ( P 〈 0.05 ) ,and the low dosage group ( P 〈 0.01 ). But in the acute gastric mueosol injury model group no obvious effect was observed ( P 〉 0.05 ). Conclusion Houtougu gastrointestinal health oral liquid has protective effect on chronic gastric ulcer in rats.
出处
《现代食品与药品杂志》
2007年第6期22-24,共3页
JOurnal of Modern Food and Pharmaceuticals
关键词
猴头菇胃肠保健口服液
胃黏膜损伤
保护功能
Houtougu gastrointestinal health oral liquid
gastric mueosa
lesion
protective effect