摘要
术后恶心呕吐(PONV)是最常见的麻醉后不良反应之一。PONV增加了术后患者的不适,且严重时会引起其他并发症,同时增加了患者的医疗费用,因此防止PONV的发生对患者十分重要。在引起PONV的众多原因中,麻醉是十分重要的因素。虽有报道称使用吸入麻醉药会显著增加PONV的发生率,但为了减少大剂量单一用药的不良反应,作者仍推荐在全身麻醉中采用静吸复合麻醉的方法。这篇文章综述了PONV的病理生理机制,并对各种静脉和吸入麻醉药物引起PONV的作用进行比较,希望能使麻醉医生对各种麻醉药物的致吐性有较全面的了解,更加合理的选择药物,有效降低患者PONV的发生。
Postoperative nausea and vomiting (PONV) are among the most frequent complications after general anesthesia. Avoiding these symptoms is of importance for most patients; PONV is not only a major source of discomfort for patients but also a cause of additional costs for the patients and the health care provider. Among all the risk factors of the PONV, anesthetic is the most important one. It' s reported that the cumulative incidence of PONV is significantly more frequent with the use of inhalational anesthetics. In order to reduce the side effect of single drug the authors advocate the combination of intravenous anesthetics with inhalatlonal anesthet- ics in general anesthesia. In this review, the authors summarize the brief pathophysiological mechanism of PONV and compare the in- fluence of the intravenous anesthetics with inhalational anesthetics on PONV. An anesthetist will get more idea of the side effect of every narcotic on PONV in this paper and will make a more reasonable selection, so that the PONV will be effectively prevented.
出处
《国际麻醉学与复苏杂志》
CAS
2007年第6期536-539,共4页
International Journal of Anesthesiology and Resuscitation