摘要
从中药三叉苦(Evodia lepta(Spreng.)Merr.)的地上部分分离鉴定了4个化合物。通过光谱解析和结构沟通的方法确定了它们的结构。其中3个为新化合物,依次命名为leptin A(Ⅰ)、leptin B(Ⅱ)和leptin C(Ⅲ)。另外一个已知化合物为异吴茱萸酮酚(Ⅳ)。
Three new 2,2-dimethylchroman derivatives named leptin A(I), leptin B(II), and leptin C(III), along with a known compound-isoevodionol (IV), have been isolated from the aerial parts of Evodia lepta (Spreng.) Merr. Based on the spectroscopic analysis and chemical evidence, compounds I,II,III were elucidated as cis-3, 4, 5-trihydroxy-6-acetyl-7-methoxy-2, 2-dimethylchroman, trans-3,4,5-trihydroxy-6-acetyl-7-methoxy-2,2-dimethylchroman and 3,5-dihy-droxy-4-ethoxy-6-acetyl-7-methoxy-2,2-dimethylchroman, respectively.
