摘要
目的:探讨电针合并阿立哌唑治疗精神分裂症阴性症状的疗效和安全性。方法:对于2005年1月至2006年12月入院的以阴性症状为主的精神分裂症患者60例,随机分为电针合并阿立哌唑治疗组(研究组)和单用阿立哌唑治疗组(对照组)各30例,疗程12周。采用阳性与阴性症状量表(PANSS)、副反应量表(TESS),在治疗前和治疗后2、4、8、12周末各评定1次,评定疗效和不良反应。结果:研究组疗效优于对照组(P<0.05),起效时间早于对照组(P<0.05),而两组不良反应评定无显著性差异(P>0.05)。结论:电针合并阿立哌唑治疗以阴性症状为主的精神分裂症,起效快,安全性高。
Objective:To explore the efficacy and safety of electric acupuncture combined with aripiprazole in treating negative symptoms of schizophrenia. Methods:60 patients with negative symptoms of schizophrenia who were hospitalized in Nanping Psychiatry Hospital between January 2005 and December 2006,they were randomly assigned to two groups, one group was treated by electric acupuncture combined with aripiprazole (research group) n = 30,the other group was treated by the simple aripiprazole (control group)n =30, for 12 weeks. Effects and side effects were assessed with the Positive and Negative Symptom Scale (PANSS) and Treatment Emergent Symptonl Scale(TESS) before and after respectively 2,4,8,12 weeks treatment. Results: The efficacy of research group is better than the control group( P 〈 0.05 ). And the research group took effect more early time than the control group( P 〈 0.05 ) But there was no different in side effect between the two groups (P 〉 0.05 ). Conclusions : Electric acupuncture combined with aripiprazole in treatment of negative symptoms of schizophrenia has faster efficacy and better safety.
出处
《中国民康医学》
2008年第1期7-10,共4页
Medical Journal of Chinese People’s Health
关键词
阿立哌唑
电针治疗
精神分裂症
阴性症状
Aripiprazole
Electric acupuncture
Schizophrenia
Negative symptoms