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IgA肾病湿热证与临床病理的相关性研究 被引量:23

Study on the Relationship Between Damp-heat Syndrome and Clinical Pathology in IgA Nephropathy Patients
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摘要 目的:研究IgA肾病湿热证与临床病理的相关因素分析。方法:分析53例IgA肾病湿热证与53例非湿热证患者的临床及肾脏病理资料。结果:IgA肾病湿热证的中医宏观辨证中最常见的症候是咽喉肿痛,其次是小便黄赤、灼热或涩痛不利;临床伴肉眼血尿,有感染诱因者比非湿热证组多见,表现为肾病综合征比非湿热证组少;血C反应蛋白水平显著高于非湿热证组;肾小球细胞增殖积分显著高于非湿热证组。结论:IgA肾病湿热证与临床指标及肾组织病理有一定相关性,中医宏观辨证与西医微观辨证的结合将更有利于揭示IgA肾病湿热证的本质,为证的客观化研究提供一定依据。 Objective: To observe the relationship between damp - heat syndrome and clinical pathology in patients with IgA nephropathy ( IgAN ). Methods : We collect the clinicopathological materials of 53 patients with damp - heat syndrome, and 53 patients with non damp - heat syndrome. Result: In patients with damp - heat syndrome, swelling and aching of throat was the symptom most commonly seen;often accompanied with gross hematuria and had more inducement of infection, few with nephrotic syndrome. Compared with patients of non damp - heat syndrome, plasma levels of creactive protein( CRY), was obviously higher, and scores of glomerular cell multiplication significantly higher. Conclusion : Damp - heat syndrome of IgAN are correlated with certain clinical parameters and renal pathological changes. The combination of TCM hnlistic syndrome differentiation and Western medicinal micro - differentiation is more favorable for making clear the nature of damp - heat syndrome of IgAN. It may provide some guidances for the objectivise of "syndrome".
出处 《中华中医药学刊》 CAS 2008年第1期178-180,共3页 Chinese Archives of Traditional Chinese Medicine
关键词 IGA肾病 湿热证 中医辨证 IgA nephropathy damp- heat syndrome syndrome diferentiation of TCM
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参考文献3

  • 1[1]Li LS,Liu ZH.Epidemiologic data of renal diseases from a single unit in China:analysis based on 13,519 renal biopsies[J].Kidney Int,2004,66(3):920-923.
  • 2[4]Lee SM,Rao VM,Franklin WA,et al.IgA nephropathy:morphologic predictors of progressive renal diseases[J].Hum Pathol,1982,13:314-322.
  • 3[5]Katafuchi R,Kiyoshi Y,Oh Y.Glomerular score as a prognosticatorin IgA nephropathy:its usefulness and limitation[J].Clin Nephrol,1998,1:1-8.

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