摘要
目的观察奥扎格雷钠联合灯盏花素对2型糖尿病性周围神经病的临床疗效。方法将85例2型糖尿病性周围神经病患者随机分为治疗组(43例)和对照组(42例)。在积极控制血糖的基础上,治疗组用奥扎格雷钠注射液80mg溶于生理盐水250ml中静脉滴注,每日2次,灯盏花素注射剂50mg溶于生理盐水250ml中静脉滴注,每日1次,连用14 d;对照组用维生素B1100 mg和维生素B12500μg肌注,每日1次,烟酸50 mg和地巴唑50 mg口服,每日三次连用14 d。比较两组治疗前后症状、体征、神经传导速度的变化。结果与对照组相比,治疗组患者症状和体征明显改善(P<0.05),感觉及运动神经传导速度有显著提高(P<0.05)。结论奥扎格雷钠与灯盏花素联合用药对治疗糖尿病性周围神经病疗效明显。
Objective To observe the therapeutic effects of Azagrel and Breviscapine on diabetic peripheral neuropathy. Methods Eighty- five diabetes mellitus（type 2）patients with diabetic peripheral neuropathy were selected and divided randomly into two groups. On the base of control of blood glucose, the test group were given sodium ozagrel 80mg dissolved in 0.9 % sodium chloride injection 250ml twice a day intravenously and Dengzhanhua 50mg in 250 ml in 0.9 % sodium chloride injection 250ml intravenously once a day for 14 days. The control group was treated with intramuscular injection VitBl 100mg and VitB12 500ug ,once a day; at the same time 50mg nicotinic acid and 50mg dibazal was given orally three times a day for 14 days. Results The clinical symptom and objective signs in the treatment group were obviously ameliorated as compared to the control groups P 〈0.05）, There is much improvement in the speed of the feeling and the motor nerve （P 〈 0.05）. Conclusions It is an effective method using Azagrel and Breviscapine to treat diabetic peripheral neuropathy.
出处
《湖北民族学院学报（医学版）》
2007年第4期27-29,共3页
Journal of Hubei Minzu University(Medical Edition)
