摘要
目的探讨短波热疗对荷VX2肿瘤的抑制作用。方法选择一级新西兰兔49只,随机分成热化组(RH)13只、热疗组(R)13只、化疗组(H)12只和空白对照组(K)11只。移植VX2肿瘤10天后,对RH组施加热疗和化疗,R组施加热疗,H组施加化疗,K组不作任何处理,监测肿瘤的变化。结果RH组、R组、H组和K组平均瘤重为9.1 g、29.81 g、16.62 g和29.93 g。RH组瘤重极显著小于对照组(P<0.01),并显著小于H组(P<0.05)。肿瘤平均大小为:7.81 cm3、26.28 cm3、11.66 cm3和30.94 cm3,RH组肿瘤平均体积比H组小,但无显著性差异。结论短波热疗结合化疗对兔VX2肿瘤的抑制作用明显高于单纯化疗。单纯热疗未见对肿瘤有明显的抑制作用。
Objective To study the restraint of heat therapy of short wave on VX2 tumor in rabbits. Method 49 New Zealand rabbits （CV） were randomly divided into 4 groups-13 rabbits in heat chemotherapy group （RH）, 13 rabbits in heat therapy group（ R）, 12 rabbits in chemotherapy （H）, 11 rabbits in control group （K）. The rabbits had been inoculated with VX2 cells. After 10 days, group RH underwent heat therapy and chemotherapy; group R underwent heat therapy; group H underwent chemotherapy; group K underwent nothing. Meanwhile, the ehanges of these tumors were observed and measured. Result The average tumors weights of groups RH, R, H, K were 9. 1 g, 29.81g, 16. 62g, 29. 93g respectively. The weight of group RH was significantly lighter than that of group K （P 〈0. 01 ）, and significantly lighter than that of groupH （P〈0.05）. The average volumes of tumors of groups RH, R, H, K were 7.81 cm^3, 26.28 cm^3, 11.66 cm^3, 30. 94 cm^3 respeetively. The volume of group RH was smaller than that of group H, but the difference was not significant. Conclusion Heat therapy of short wave and chemotherapy can restrain the VX2 tumor growth on the rabbits greatly, and the effect is better than that of chemotherapy alone. The heat therapy alone did not significantly restrain VX2 tumor growth.
出处
《四川动物》
CSCD
北大核心
2008年第1期147-149,共3页
Sichuan Journal of Zoology
关键词
热疗
短波
VX2肿瘤
heat therapy
short wave
VX2 tumor
