摘要
目的为了拓展纤维蛋白基生物材料的临床应用,拟开展深入的细胞生物学研究。方法查阅近年来国内外相关资料,全面了解和掌握纤维蛋白国内、外发展现状。结果从纤维蛋白原结构与功能、蛋白胶的临床应用、支架材料用于组织工程和复合其他生物医用材料4个方面获得认知,发现纤维蛋白在各方面均具有很强的研究延伸性和实际应用性。结论纤维蛋白不仅可用作外科止血剂、封闭剂,同时在作为组织工程支架、药物传递载体以及复合材料方面均具有极大的开发潜力。
Objective To broaden the clinical uses of fibrin-based biomaterials and to develop further study in cell biology and to comprehensively understand and master related knowledge with regard to the present development status of fibrin. Methods Many relevant domestic and international papers were reviewed to make a summary. Results Recognization was obtained from four aspects, which were structure and function of fibrinogen, clinical use of fibrin, fibrin scaffold for tissue engineering, and compounding biomaterials of fibrin. It showed that every aspect had great research extension and practical application. Conclusion Besides a surgical hemostat and sealant, fibrin has great potentials in playing roles of tissue engineering scaffold, drug delivery vehicle, and compounding material.
出处
《中国修复重建外科杂志》
CAS
CSCD
北大核心
2008年第2期188-191,共4页
Chinese Journal of Reparative and Reconstructive Surgery
