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未行预防性侧颈清扫的CN0甲状腺乳头状癌的临床转归 被引量:5

Clinical prognosis of patients with CN_0 papillary thyroid carcinoma without prophylactic neck dissection
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摘要 目的:研究未行预防性侧颈清扫的CN0甲状腺乳头状癌(papillary thyroid carcinoma,PTC)患者初次手术后出现临床侧颈淋巴结转移的发生率。方法:回顾性分析复旦大学附属肿瘤医院1991年11月—2001年11月收治的未行预防性侧颈清扫的CN0甲状腺乳头状癌患者380例临床资料。结果:380例患者中出现临床同侧颈淋巴结转移的有8例再行侧颈淋巴结清扫术;术前行颈CT检查未提示有侧颈淋巴结肿大的56例在术后随访中无临床侧颈淋巴结转移。病灶大小、年龄、中央区淋巴结转移情况均不是预示随访中出现侧颈淋巴结转移的高危患者因素。结论:对CN0期甲状腺乳头状癌患者不主张行预防性侧颈清扫,可观察;术前CT检查能减少术后侧颈淋巴结的转移率。 Objective:To determine the incidence of lateral lymph node (LN) metastasis in patients with CN0 papillary thyroid carcinoma who did not undergo prophylactic neck dissection after initial surgery. Methods:Three hundred and eighty patients diagnosed as CN0 papillary thyroid carcinoma were admitted in our hospital from Nov. 1991 to Nov. 2001. They did not receive prophylactic ipsilateral neck dissection. Their clinical data were analyzed retrospectively. Results:LN metastasis in ipsilateral cervical area was present in 8 of 380 patients who were given second lateral elective neck dissection. Fifty six patients with lateral cervical lymphadenectasis diagnosed with preoperative CT scan had negative lateral cervical LN metastasis during follow-up period. The size of the lesions, the age of the patients, the status of central compartment LN metastasis were not risk factors for lateral cervical LN metastasis during follow-up period. Conclusion:Prophylactic neck dissection is not recommended for patients with CN0 papillary thyroid carcinoma but close observation is necessary. Preoperative CT scan could decrease the LN metastasis rate in lateral cervical area postoperatively.
出处 《肿瘤》 CAS CSCD 北大核心 2008年第1期80-82,共3页 Tumor
关键词 甲状腺肿瘤 淋巴结清扫术 外科手术 Thyroid neoplasms Neck dissection Surgical procedures,operative
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参考文献6

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二级参考文献4

  • 1汪卫东,中华放射学杂志,1995年,29卷,543页
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  • 4李树玲,国外医学.肿瘤学分册,1984年,4卷,193页

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