摘要
目的探讨血清TNF-α和IL-6水平对急性胰腺炎的预测价值。方法急性胰腺炎患者36例,其中重症13例,轻症23例,健康对照组16例。血清TNF-α和IL-6水平采用ELISA方法检测。结果重症和轻症急性胰腺炎患者的血清TNF-α和IL-6水平明显高于正常对照组(P<0.05),且重症急性胰腺炎患者亦明显高于轻症急性胰腺炎患者(P<0.05)。结论急性胰腺炎时血清中TNF-α和IL-6浓度升高,它们可以用来判断急性胰腺炎严重程度。
Objective To investigate the effects of serum TNF-α and IL- 6 on evaluating the severity of acute pancreatitis. Methods Thirty - six patients with acute pancreatitis were divided into severe acute pancreatitis group（ SAP, n = 13） and mild acute pancreatitis group（ MAP, n =23）. Sixteen healthy individuals were chosen as control group. The serum TNF - α amd IL - 6 were detected by ELISA. Results The serum levels of TNF - α and IL - 6 were significantly higher in SAP and MAP groups than those in healthy control group （ P 〈 0. 05 ）. In addition, the levels of TNF - α and IL - 6 were also markedly increased in SAP group compared with those in MAP group （ P 〈 0. 05 ）. Conclusion There were positive relationship between the concentration of TNF - α and IL - 6 and the severity of acute pancreatitis. They can be used to predict the severity of acute pancreatitis in early stage.
出处
《医药论坛杂志》
2007年第24期33-34,37,共3页
Journal of Medical Forum
