摘要
目的研究经灵芝发酵后的夜交藤提取物(简称灵藤提取物)对小鼠镇静催眠的作用和免疫功能的影响。方法观察灵藤提取物对小鼠自发活动,对戊巴比妥钠诱导小鼠睡眠时间和睡眠个数,以及对小鼠脾、胸腺器官和巨噬细胞吞噬能力的影响。结果灵藤提取物(5g/kg,10g/kg)能抑制小鼠的自发活动,延长戊巴比妥钠诱导的小鼠睡眠时间,增加小鼠睡眠个数,也能显著增加小鼠脾脏、胸腺的重量,增加巨噬细胞吞噬能力。结论灵藤提取物具有镇静催眠、提高免疫力的作用。
Objective To study the effects of extract of tuber fleeceflower stem fermented by lucid ganoderma fungus （Lingteng extractive） on sleeping and immune function in mice. Methods The effects of Lingteng extractive on spontaneous activity of mice, dormancy-number and dormancy-time of mice induced by pentobarbital sodium were observed, and the spleen index, thymus index and phagocytosis ability of macrophages with different doses of Lingteng extractive were determined. Results Compared to control group, Lingteng extractive （5 g/kg, 10 g/kg） could inhibit the spontaneous activity, increase dormancy-number and dormancy-time of mice induced by pentobarbital sodium, and it could also obviously increase the spleen index, thymus index and strengthen the phagocytosis ability of macrophages. Conclusion Lingteng extractive has the effects on sleeping and immune function in mice.
出处
《食品与药品》
CAS
2008年第1期29-31,共3页
Food and Drug
关键词
夜交藤
灵芝
镇静催眠
免疫调节
戊巴比妥钠
小鼠
tuber fleeceflower stem
lucid ganoderma fungus
sedation and hypnotism
immune modulation
pentobarbital sodium
mice
