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高温高湿环境兔颅脑火器伤后HSP70的变化 被引量:1

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摘要 目的:研究热休克蛋白70(HSP70)在高温高湿环境下颅脑火器伤后的变化及其作用。方法:采用高温高湿颅脑枪伤模型,新西兰大白兔24只,随机分成常温对照组:(22.0±0.5)℃、RH50%,常温枪伤组:(22.0±0.5)℃、RH50%,高温高湿枪伤组(39.0±0.5)℃、RH80%~85%,每组8只。采用Westernblot法检测脑组织、淋巴细胞HSP70,应用化学发光和X线片显示,凝胶图像分析仪定量分析。结果:颅脑枪伤受高温高湿环境作用后,大脑皮层、下丘脑和淋巴细胞的HSP70显著增高;淋巴细胞中的HSP70与大脑皮层、下丘脑的变化趋势相一致。结论:脑组织和淋巴细胞中HSP70在高温高湿环境颅脑火器伤时显著增加。
作者 钱畅 黄柒金
出处 《广西医科大学学报》 CAS 北大核心 2007年第6期890-891,共2页 Journal of Guangxi Medical University
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