摘要
采用国产安吖啶(m-amsacrine,AMSA)联合方案治疗急性白血病(AL)30例;急性淋巴细胞白血病(ALL)6例,急性非淋巴细胞白血病(ANLL)24例;初治21例,复治9例。总的CR率为76.7%;ALL的CR率为66.6%,ANLL的CR率为79.2%,初、复治病例的CR率分别为80.9%、66.7%。主要毒性为骨髓抑制,其次为脱发、食欲下降、恶心、呕吐、口腔粘膜炎、静脉炎等。
Patients with acute leukemias, 6 acute lymphoblastic leukemias(ALL) and 24 acute nonlymphoblastic leukemias(ANLL), were treated with combination chemotherapy including domestic Amascrine(m AMSA). The total CR rates was 76.7%(66.6% in ALL, 79.2% in ANLL). The CR rates of previously untreated and treated patients were 80.9% and 66.7%, respectively. The chief toxicity was myelosuppression, aloecia, nausea, vomiting, mucositis and phlebitis.
出处
《白血病》
1997年第2期68-70,共3页