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煤工尘肺患者血清中抵抗素和瘦素水平及临床意义

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摘要 目的探讨煤工尘肺患者血清中抵抗素和瘦素水平及意义。方法选择85例煤工尘肺患者(煤工尘肺组)作为观察对象,并以46例井下非尘肺工人(井下对照组)及40例井上非尘肺工人(井上对照组)作为对照,采用酶联免疫吸附双抗体夹心法检测血清中抵抗素和瘦素水平,并分析与体重指数(BMI)的关系。结果与井上对照组及井下对照组比较,煤工尘肺患者血清中抵抗素和瘦素水平均明显降低,差异均有统计学意义(P〈0.01);BMI较差及正常的煤工尘肺患者血清中抵抗素、瘦素水平明显低于井上对照和井下对照,差异有统计学意义(P〈0.05)。抵抗素和瘦素均与BMI呈正相关关系(r=0.43、r=0.47,P〈0.01)。结论煤工尘肺患者血清中抵抗素和瘦素水平下降,BMI较差时下降更明显。
出处 《中华劳动卫生职业病杂志》 CAS CSCD 北大核心 2008年第1期52-53,共2页 Chinese Journal of Industrial Hygiene and Occupational Diseases
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