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蛋白质组学在阿尔茨海默病研究中的应用

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摘要 阿尔茨海默病(AD)是一种中枢神经系统退行性疾病.主要表现为进行性认知功能和记忆功能障碍,发病年龄为40~90岁,大部分在65岁以后。是中老年人群中痴呆最常见的病因。德国病理学家Alois Alzheimer于1906年首次报告了阿尔茨海默病的主要临床和组织病理学改变。此后的30年在临床诊断标准的设立及神经病理学等方面有了巨大发展,但阿尔茨海默病的发病机制仍不十分清楚。
出处 《中国现代神经疾病杂志》 CAS 2008年第1期8-11,共4页 Chinese Journal of Contemporary Neurology and Neurosurgery
基金 国家重点基础研究发展规划(973计划)资助项目(项目编号:2006cb500700)
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