摘要
目的分析医院阴沟肠杆菌感染的临床分布及耐药性,以指导临床合理用药。方法对医院近2年分离出的阴沟肠杆菌的临床分布特点及耐药情况进行总结分析。结果2005年1月-2006年12月共分离出148株阴沟肠杆菌,菌株来源主要为痰液、尿液,分别占53.4%、16.2%;菌株分布于多个病区;阴沟肠杆菌对碳青酶烯类、头孢吡肟、哌拉西林/他唑巴坦、头孢哌酮/舒巴坦、莫西沙星的敏感性较高。结论阴沟肠杆菌主要引起呼吸道、尿路感染;对三代头孢菌素耐药严重,呈多药耐药性,亚胺培南仍为治疗阴沟肠杆菌严重感染的首选用药。
OBJECTIVE To investigate the clinical distribution and antimicrobial resistance of infections caused by Enterobacter cloacae in our hospital, for guiding the clinical application of antibiotics reasonably. METHODS Retrospective analysis of the drug resistance situation and specimen distribution was made to the E. cloacae isolated from our hospital in the recent 2 years. RESULTS Totally 148 strains of E. cloacae were isolated between Jan 2005 and Nov 2006 ,the percentages of these strains isolated from sputum, and urine were 53.4% and 16.2%, respectively; the 148 strains of E. cloacae distributed in many wards, were more sensitive to carbapenem, cefepime, piperacillin/tazobactam, cefoperazone/sulbactam, and moxifloxacin. CONCLUSIONS E. cloacae mainly causes infections of respiratory tract and urinary tract in clinic. E. cloacae is multidrng resistant and severely resistant to third generation cephol.osporins, imipenem remains to be the first choice to treat the severe infection which caused by E. cloacae.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2008年第2期264-266,共3页
Chinese Journal of Nosocomiology
关键词
阴沟肠杆菌
耐药性
医院感染
Enterobacter cloacae
Antimicrobial resistance
Hospital infection
