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阿托伐他汀类药物治疗血脂紊乱的临床观察 被引量:14

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摘要 目的观察阿托伐他汀治疗高血脂症的临床疗效。方法选择符合条件的高血脂症住院患者60例,给予口服阿托伐他汀10mg,每日1次,患者在治疗期间进行标准的低胆固醇饮食维持合理的膳食。所有患者于治疗前及治疗后2周、4周,采用酶联免疫吸附法测定血浆总胆固醇(TC),低密度脂蛋白胆固醇(LDL—C)及甘油三脂(TG)的浓度,同时用药前后检测肝、肾功能、血浆肌酸激酶(CK)、血常规、心电图各一次。结果60例高脂血症患者中,36例患者在服用阿托伐他汀钙片2周后,TC、LDL—C及TG有不同程度的改善。有效率为60%。有24例患者降低效果未达标,治疗4周后,14例患者的TC、LDL—C及TG指标中有1~2项达到有效,总有效率为83.3%。有4例患者服用阿托伐他汀钙片TC、LDL-C及TG下降不明显。经统计学分析。治疗前后有显著差异(P〈0.05)。结论阿托伐他汀类药物治疗高血脂症患者取得了较好的疗效。
出处 《实用药物与临床》 CAS 2008年第1期14-15,共2页 Practical Pharmacy and Clinical Remedies
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