摘要
背景:上消化道出血并发急性脑梗死的病例鲜见报道,应总结其临床特点。目的:探讨上消化道出血并发急性脑梗死的临床特点。方法:分析24例上消化道出血并发急性脑梗死患者的临床特点。结果:本组24例患者的平均年龄63.0岁,9例(37.5%)上消化道出血病因为肝硬化,14例(58.3%)为大出血,14例(58.3%)使用抗纤溶药物,21例(87.5%)伴高血压、高血脂、冠心病、糖尿病等与动脉硬化有关的因素。发生脑梗死的平均时间为上消化道出血后3.6d,大面积梗死多见。结论:对上消化道出血伴有与动脉硬化有关的因素(高血压、高血脂、冠心病、糖尿病等)以及既往有肝硬化史的老年患者,尤其是大出血者,应认识到并发急性脑梗死的危险,出血后3d左右脑梗死的发生率最高。治疗应禁用或慎用抗纤溶药。
Upper gastrointestinal hemorrhage （UGH） complicated with acute cerebral infarction （ACI） is rarely reported, and its clinical characteristics should be summarized. Aims： To investigate the clinical characteristics of UGH complicated with ACI. Methods： Clinical characteristics of 24 patients with UGH complicated with ACI were analyzed. Results： The average age of 24 patients was 63.0 years old. UGH was due to liver cirrhosis in 9 cases （37.5%）. lg （58.3%） patients had extensive hemorrhage, 14 （58.3%） were given antifibrinolytic agents. 21 patients （87.5%） were associated with hypertension, hyperlipidemia, coronary heart disease or diabetes mellitus. The average time of ACI occurrence was 3.6 days after UGH, and extensive infarction were frequently seen. Conclusions： For senile UGH patients associated with hypertension, hyperlipidemia, coronary heart disease, diabetes mellitus and liver cirrhosis, especially those with extensive hemorrhage, the risk of ACI should be on the alert. The occurrence of ACI is highest about 3 days after UGH. Antifibrinolvtic agents should not be administrated, or mav be used cautiouslv.
出处
《胃肠病学》
2008年第1期49-50,共2页
Chinese Journal of Gastroenterology
关键词
上消化道出血
脑梗塞
并发症
Upper Gastrointestinal Hemorrhage
Brain Infarction
Complication
