摘要
人体滑膜关节中,天然关节软骨具有多重不可替代的特殊功能和重要作用。本研究从仿生学的视角,综述关节软骨的生物化学、组织形态学、病理学特征,以及生物材料学、生物力学和生物摩擦学性质;从结构、材料、功能三个方面对关节软骨进行宏、微观层次的仿生设计,建立关节软骨仿生设计模型;为带有"软垫轴承"的新型人工关节,以及仿生人工软骨的创新设计与制造,提供理论和实践基础。
Natural articular cartilage is well known as a special connective tissue with multiple effects and functions, which are important and irreplaceable, in human synovial joints. Biomedical, histological and pathological characteristics of articular cartilage, as well as biomaterial, biomeehanical and bio-tribological properties thereof, are summarized from a novel aspect of bionics. Bionic design of articualr cartilage at macro-level and micro-level is carried out from three aspects, i.e., structure, material, and function; and a bionic design model of articular cartilage is set up. As a result, this basic research would be helpful to providing theoretical and practical basis for innovational design and manufacturing of newstyle artificial joint with “soft-cushion bearing”, and of bionic artificial cartilage.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2008年第1期182-185,共4页
Journal of Biomedical Engineering
基金
国家自然科学基金资助项目(30300078)
关键词
关节软骨
仿生设计
人工关节
人工软骨
Articular cartilage Bionic design Artificial joint Artificial cartilage
