摘要
目的评价α-硫辛酸联合前列腺素E1对2型糖尿病合并周围神经病变的治疗效果。方法将60例糖尿病性周围神经病变患者随机分为2组,治疗组给予α-硫辛酸600 mg、前列腺素E110μg治疗2周,对照组每日给予前列腺素E110μg治疗2周。治疗前后分别进行神经病变症状TSS评分及感觉定量比较。结果经过2周治疗后,两组患者的TSS评分及感觉定量明显改善(P<0.05),无严重药物不良反应。与对照组相比,治疗组改善更明显(P<0.05)。结论临床使用α-硫辛酸联合前列腺素E1治疗糖尿病合并周围神经病变安全有效。
Objective To evaluate the effect of alpha-lipon and PGE1 on diabetic peripheral neuropathy. Methods Sixty patients with diabetic peripheral neuropathy were randomly divided into two groups. The treatment group were treated with alpha-lipon 600mg and PGE1 10μg daily for two weeks. The control group were treated with PGE1 10μg daily for two weeks. All patients were evaluated with TSS score and sense value before and after the treatment. Results Compared with the control group, the treatment group had more significant improvement of TSS score and sense value after the treatment for two weeks（ P 〈0.05）. No patients had severe drug side reaction. Conclusions Treatment of alpha-lipon and PGE1 on patients with diabetic peripheral neuropathy is safe and effective.
出处
《中国临床保健杂志》
CAS
2008年第1期29-30,共2页
Chinese Journal of Clinical Healthcare
