期刊文献+

精神分裂症患者脑供血情况与认知功能的研究 被引量:8

Study of brain blood supply and cognitive function in schizophrenia
下载PDF
导出
摘要 目的:探讨精神分裂症患者脑供血情况与认知功能之间的关系。方法:对精神分裂症患者100例进行听觉事件相关诱发电位(P300)检查,以评价其认知功能;对认知功能检查"差"和"极差"的患者进行经颅多普勒脑血流图(TCD)检查记录血流峰值及脉动指数,以了解其脑供血情况。结果:100例精神分裂症患者P300检查中有83例认知功能为"差"到"极差",这83例患者TCD检查结果显示,大脑中动脉和大脑前动脉脉动指数均显著高于我国正常成人常模。结论:精神分裂症患者认知功能普遍较差,可能与其大脑中动脉、大脑前动脉血管舒缩调节功能下降导致大脑前额叶供血不足有关。 Objective:To investigate the relationship between brain blood supply and cognitive function in schizophrenia. Method: 100 patients with schizophrenia were selected and made them had test of auditory evoked event-related potential (P300).Transcranial doppler cerebral blood flow chart (TCD) was measured for those get- ting scores of poor or very poor in cognitive function examination to find out the state of blood supply in the brain by recording the peak flow of blood and pulsatility index. Results: 83 out of 100 patients with schizophrenia got scores of poor or very poor in cognitive function in P300 test. TCD examinations of those 83 patients showed the pulsating index in medial cerebral artery and anterior cerebral artery were higher than Chinese normal. Conclusion: Schizophrenic patients usually has poor cognitive function, which may be related to short blood supply in prefrontal brain resulted from lower vasomotory adjusting function of medial cerebral artery and anterior cerebral artery.
出处 《临床精神医学杂志》 2008年第1期30-31,共2页 Journal of Clinical Psychiatry
关键词 精神分裂症 认知功能 经颅多普勒脑血流图 schizophrenia cognitive function transcranial doppler cerebral blood flow chart
  • 相关文献

参考文献10

二级参考文献12

  • 1张明岛 陈兴时.脑诱发电位学(第2版)[M].上海:上海科技教育出版社,1997.265-266.
  • 2张源昌 等.脑血管疾病(第2版)[M].北京:人民卫生出版社,1984.26-27.
  • 3中华医学会全国脑电图及临床神经生理学会.脑电图描绘的最低要求[J].脑电图学与神经精神疾病杂志,1990,6:64-66.
  • 4Sutton S. Evoked potential Correlates of Stimulus Uncertaity. Science,1965,150:1187.
  • 5Shajahan PM, O' Carroll RE, Ghtms ME, et al. Correlation of auditory‘Oddball’ P300 with verbal memory deficits in schizophrenia. Psychological Medicine, 1997,27:579-586.
  • 6张明岛 陈兴时.脑诱发电位学:第2版[M].上海:上海科技教育出版社,1997.12-13,258-259,265-266,265-267.
  • 7Dr. M. Odawara. Decreased cerebral blood perfusion in an NIDDM patient with an A-to-G mutation in the mitochondrial gene; a possible contribution to cognition deficits in diabetes mellitus[J] 1995,Diabetologia(8):1004~1005
  • 8顾慎为.经颅多普勒检测与临床[M]上海医科大学出版社,1993.
  • 9(美)图 尔(Toole,J.F.)著,重庆医科大学神经疾病研究室.脑血管疾病[M]重庆出版社,1989.
  • 10朵振顺,魏利华,苏传良,孙晋华,李兵,武翠梅.血流变学的变化对颅内动脉血流的影响[J].山西医学院学报,1991,22(4):241-242. 被引量:5

共引文献55

同被引文献79

引证文献8

二级引证文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部