摘要
为了探讨宫内铅暴露与新生儿神经行为发育的关系，选择了北京地区１０１例新生儿，以脐血铅含量作为新生儿宫内铅暴露的指标，新生儿神经行为评分作为效应指标。结果：新生儿脐血铅含量与神经行为总分及行为能力评分间存在负相关关系。以脐血铅含量０．４８μｍｏｌ／Ｌ为分界，高铅组与相对低铅组新生儿行为能力评分差异有显著性，其行为能力分项评分结果表明，非生物听定向反应、生物性视和听定向反应两组比较差异有显著性。提示：宫内铅暴露对新生儿神经行为发育，特别对视和听功能可产生不良影响。
Umbilical blood lead level, as an indicator for intrauterine exposure to lead, and neurobehavioral score, as an effect indicator, were determined in 101 neonates in Beijing area to explore the relationship between intrauterine lead exposure and neonatal neurobehavioral development. Results revealed that there was a negative relationship between neonatal umbilical blood lead level and their neurobehavioral score and behavioral ability. With umbilical blood lead level of 0.48 μmol/L as a cutoff value, there was a significant difference in neonatal behavioral ability score between groups of high and low blood lead levels. There also were significant differences in nonbiologically auditory and biological visual and auditory orientation reaction. It suggests that intrauterine lead exposure can cause adverse effects on neonatal neurobehavioral development, especially on their visual and auditory function.
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
1997年第4期215-217,共3页
Chinese Journal of Preventive Medicine
基金
卫生部科学基金
