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通心络对急性冠脉综合征患者血清炎性因子的影响

Influence of Tongxinluo on Serum Inflammatory Factors in Patients with Acute Coronary Syndrome
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摘要 目的观察通心络胶囊对急性冠脉综合征患者血清炎性因子的影响。方法60例经临床诊断为急性冠脉综合征的患者,随机分为对照组和治疗组(各30例)。对照组按急性冠脉综合征常规治疗,不予任何降脂药;治疗组除给予常规治疗外,加服通心络6粒/天。用酶联免疫吸附法分别检测两组患者治疗前后血清C反应蛋白和白细胞介素6水平。结果治疗组治疗后C反应蛋白由治疗前的(11.64±9.26)mg/L降至(8.11±6.20)mg/L、白细胞介素6由治疗前的(11.36±9.20)pg/ml降至(8.59±6.01)pg/ml,有显著性差异(P<0.01)。结论通心络具有抗炎和稳定斑块的作用。 Objective To observe the influence with acute coronary syndrome (ACS). Methods Sixty of tongxinluo on serum inflammatory factors in patients patients with ACS were randomized into two groups, group treated with routine therapy (control group) (n = 30) and group treated with to uo (treatment group) ( n = 30). The control group just only accepted routine therapy of ACS, and the treatment group accepted tongxinluo six capsula every day. The concentration of serum C reactive protein(CRP) and interleukin -6 (IL -6)of two groups were measured by ELISA. Results The concentration of CRP and IL -6 decreased significantly in treatment group ( P 〈 0.01 ). Conclusion To uo has the effects of anti -inflammation and stabilizing atherosclerotic plaques.
作者 孙蓓 宋春艳
出处 《社区医学杂志》 2008年第3期4-5,共2页 Journal Of Community Medicine
关键词 急性冠状动脉综合征 通心络 血清炎性因子 C反应蛋白 白细胞介素6 Acute coronary syndrome Tongxinluo Serum inflammatory factors C reactive protein Interleukin - 6
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