摘要
目的:完善速效牛黄丸的质量标准。方法:采用薄层色谱法对栀子、黄芩和黄连进行鉴别;采用高效液相色谱法测定盐酸小檗碱含量。结果:薄层色谱中斑点清晰,易于识别。盐酸小檗碱在0.03～0.70μg(r=0.9999)范围内与峰面积呈良好的线性关系(r=0.9999),平均加样回收率为100.6%,RSD为1.1%(n=6)。结论:该方法简单、快速、具有良好的重现性。
Objective： To improve the quatity standard for suxiao Niuhuang pills. Method： The Fructus Gardenia, Radix Scutellaria and Rhizoma Coptidis were identified by TLC, the content of berberine hydrochloride was determined by HPLC. Result： The spots in TLC were quite clear. The linear range of berberine hydrochloride was 0.03 -0.70 μg（ r = 0. 999 9 ）. The average recovery was 100.6% with RSD 1.1% （n = 6）. Conclusion： The method is simple, accurate and reliable.
出处
《中国药师》
CAS
2008年第2期127-129,共3页
China Pharmacist
基金
国家自然科学基金(NO.20375010
20675084)
河北省科技攻关项目(NO.06276479B
07276407D)
中国科学院"百人计划"资助项目
