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苯那普利治疗2型糖尿病肾病的长期疗效评价 被引量:1

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摘要 目的:探讨苯那普利治疗2型糖尿病肾病的长期疗效。方法:将20例2型糖尿病肾病伴轻度高血压患者的治疗分为两个阶段,第一阶段,在2型糖尿病治疗的基础上,维持苯那普利10mg,每日1次,共6个月;第二阶段,苯那普利再增至20mg,每日1次,共6个月。每阶段,测量患者血压、体重指数、24h尿蛋白、血糖、血脂、血钾、肾小球滤过率和肾血浆流量。结果:第一阶段,患者血压、24h尿蛋白显著下降,而体重指数、血糖、血脂、血钾、肾血流动力学没有显著变化;第二阶段,患者血压、体重指数、血脂、血糖、血钾并没有显著变化,肾血流动力学维持稳定,而24h尿蛋白继续显著下降。结论:苯那普利对2型糖尿病肾病具有降血压以外的降尿蛋白的作用。
出处 《实用医学杂志》 CAS 2008年第2期203-205,共3页 The Journal of Practical Medicine
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