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男性不育症ICSI治疗的遗传风险分析 被引量：16

Genetic Risks of Intracytoplasmic Sperm Injection for Male Infertility
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摘要 近年来,ICSI对男性不育的治疗取得了极大的成功。然而,精子的遗传学异常所带来的遗传风险引起了较大的关注。在这些不育症患者中,大部分的少弱精子症患者和部分无精子症患者选择了ICSI,所以对患少弱精子症和无精子症的男性不育夫妇进行遗传学咨询与筛查,对防止这种基因缺陷的遗传具有重要意义。本综述就不育男性的遗传学缺陷发生率进行了分析。 Recently, intracytoplasmic sperm injection （ICSI） has been extremely successful in the treatment of male infertility. How-ever, the consequent transmission of sperm cytogenetic defects and genetic defects to the offspring has aroused considerable concern. Among infertile men, those with severe spermatogenic defects, including uligozoospermia and asoospermia, are mostly the subjects for ICSI. Therefore it is very important to obtain cytogenetic and chromosomal information on these infertile patients and prevent the inheritance of these genetic defects. This review offers an analysis on the genetic defects among infertile men.
作者 邵法明 朱晓斌 李铮
机构地区 宁波大学医学院附属医院泌尿外科 上海交通大学附属仁济医院泌尿外科
出处 《中华男科学杂志》 CAS CSCD 2008年第1期71-74,共4页 National Journal of Andrology
关键词 男性不育 遗传风险 卵细胞胞质内单精子注射 基因缺陷 male infertility genetic risk intracytoplasmic sperm injection genetic defect
分类号 R698.2 [医药卫生—泌尿科学]
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参考文献22

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二级参考文献16

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中华男科学杂志
2008年 第1期

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