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五指毛桃的化学成分 被引量:25

Chemical constituents from the roots of Ficus hirta
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摘要 目的:研究桑科榕属植物五指毛桃(Ficus hirta)的化学成分。方法:采用硅胶柱层析和SephadexLH-20柱层析及重结晶等方法进行分离纯化,根据理化性质和光谱数据进行结构鉴定。结果:得到12个化合物,除文献上已报道过的补骨脂素(psoralen,1)、3β-羟基豆甾-5-烯-7-酮(3β-hydroxyl-stigmast-5-en-7-one,2)、β-谷甾醇(β-sitosterol,3)、十六酸(hexadecanoic acid,5)、十八酸(octadecanoic acid,6)、芹菜素(4′,5,7-trihydroxy-fla-vone,7)、α-香树素乙酸酯(α-amyrin acetate,11)外,首次从该植物中分得的有β-胡萝卜苷(daucosterol,4)、木犀草素(luteolin,8)、牡荆苷(vitecin,9)、大黄素甲醚(physcion,10)、11-氧基-α-香树脂醇乙酸酯(11-oxo-α-amyrinacetate,12)。结论:化合物9、10、12为首次从该属植物中分离得到,4、8、9、10、12为首次从该植物中分离得到。 chemical raphy as Objective:To study the che constituents were isolated and well as recrystallization. Their mical constituents from the roots of Ficus hirta. Methods : The purified via silica gel and Sephadex LH-20 column chromatogstructures were elucidated by chemical and spectroscopic methods. Results: 12 compounds were identified, psoralen ( 1 ), 3β-hydroxyl-stigmast-5-en-7-one (2), β-sitosterol (3), hexadecanoic acid ( 5 ), octadecanoic acid ( 6 ), 4′, 5, 7-trihydroxy-flavone ( 7 ) and α-amyrin acetate (11) have been isolated from this plant, and compounds daucosterol (4), luteolin (8), vitecin ( 9), physcion (10) and 11 -oxo-α-amyrin acetate (12) have been isolated from this plant for the first time. Conclusion: The compounds 9,10 and 12 were obtained from this genus for the first time, and compounds 4,8,9,10 and 12 have been isolated from this plant for the first time.
出处 《药学与临床研究》 2008年第1期5-7,共3页 Pharmaceutical and Clinical Research
关键词 五指毛桃 化学成分 结构鉴定 Ficus hirta Chemical constituents Seructure identification
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