期刊文献+

功能影像在确定非小细胞肺癌生物靶区中的应用和展望

Application and prospect of functional imaging on defining biological target volume in non-small cell lung cancer
下载PDF
导出
摘要 准确勾画非小细胞肺癌(NSCLC)的生物靶区对非小细胞肺癌(NSCLC)三维适形调强放疗有重要的作用。PET、SPECT等功能显像以及图像融合技术的发展为准确定位NSCLC生物靶区提供了可能。本文综述了功能影像技术在NSCLC的应用,并对各种功能显像的现状进行阐明,同时展望了功能影像在非小细胞肺癌生物靶区确定和适形调强放疗中的前景和挑战。 The accurate determination of biological target volume in non-small cell lung cancer (NSCLC) is essential for the three-dimensional and intensity modulated radiation therapy. Functional imaging (PET or SPECT) and image fusion technologies is useful to delineate accurately biological target volume in NSCLC. This article reviews the application of functional imaging techniques in NSCLC and introduces the current derelopment of various functional imaging.
出处 《癌症进展》 2008年第1期36-40,共5页 Oncology Progress
关键词 功能影像 生物靶区 非小细胞肺癌 生物适形调强放疗 functional imaging biological target volume non-small cell lung cancer biological intensity - modulated radiation therapy
  • 相关文献

参考文献12

  • 1[1]Munley MT,Marks LB,Scarfone C,et al.Multimodality nuclear medicine imaging in three-dimensional radiation treatment planning for lung cancer:Challenges and prospects.Lung Cancer,1999,23 (2):105
  • 2[2]Balogh JB,Caldwell CB,Ung YC,et al.Interobserver variation in contouring gross tumour volume in carcinoma of the lung associated with pneumonitis and atelectasis the impact of 18 FDG-hybrid pet fusion.Int J Radiat Oncol Biol Phys,2000,48 (3 Suppl Ⅰ):128
  • 3[3]Bradley J,Thorstad WL,Mutic S,et al.Impact of FDG PET on radiation therapy volume Delineation in non-small-cell lung cancer.Int J Radiat Oncol Biol Phys,2004,59:78
  • 4[4]van Der Wel A,Nijsten S,Hochstenbag M,et al.Increased therapeutic ratio by 18FDG-PET CT planning in patients with clinical CT stage N2~3 M0 non-small-cell lung cancer:A modeling study.Int J Radiat Oncol Biol Phys,2005,61 (3):649
  • 5[5]Ashamalla H,Rafla S,Parikh K,et al.The contribution of integrated PET/CT to the evolving definition of treatment volumes in radiation treatment planning in lung cancer.Int J Radiat Oncol Biol Phys,2005,63 (4):1016
  • 6[6]Fox JL,Rengan R,O'Meara W,et al.Does registration of PET and planning CT images decrease interobserver and intraobserver variation in delineating tumor volumes for nonsmall-cell lung cancer? Int J Radiat Oncol Biol Phys,2005,62 (1):70
  • 7[7]Vesselle H,Grierson J,Muzi M,et al.In vivo validation of 3'deoxy-3'-[18F] fluorothymidine ([18F] FLT) as a proliferation imaging tracer in humans:Correlation of[18 F] FLT uptake by positron emission tomography with Ki-67 immunohistochemistry and flow cytometry in human lung tumors.Clin Cancer Res,2002,8 (11):3315
  • 8[8]Eschmann SM,Paulsen F,Reimold M,et al.Prognostic impact of hypoxia imaging with 18 F-misonidazole PET in non-small cell lung cancer and head and neck cancer before radiotherapy.J Nucl Med,2005,46 (2):253
  • 9李玲,于金明,邢力刚,朱慧,李国梁,方永存.^(99m)Tc-HL91 SPECT肺癌乏氧显像与放疗疗效关系的初步研究[J].中华放射肿瘤学杂志,2006,15(1):31-34. 被引量:14
  • 10[10]Furuta M,Nozaki M,Kawashima M,et al.99mTc-MIBI scintigraphy for early detection of locally recurrent non-small cell lung cancer treated with definitive radiation therapy.Eur J Nucl Med Mol Imaging,2003,30 (7):982

二级参考文献15

  • 1姚稚明,屈婉莹,周颖,朱明,朱霖.^(99m)Tc HL91 “hot spot' imaging of mice bearing human carcinoma by gamma camera and the effects of tumor necrosis on imaging[J].Chinese Medical Journal,2000(5):20-23. 被引量:10
  • 2谢新立,赵文增,刘保平,韩星敏,杜晓光,郭鹏德.^(99)Tc^m-HL91肺癌显像的临床应用[J].中华核医学杂志,2003,23(6):359-360. 被引量:30
  • 3Pauwels O, Gozy M, Van Houtte P, et al. Cross resistance and collateral sensitivity between cytotoxic drugs and radiation in two human bladder cell lines. Radiother Oncol, 1996, 39 (1):81-86.
  • 4Hill BT, Deuchars K, Hosking LK, et al. Overexpression of P-glycoprotein in mammalian tumor cell lines after fractionated X irradiation in vitro. J Nail Cancer lnst, 1990, 82 (7): 607-612.
  • 5McClean S, Hosking LK, Hill BT. Expression of P-glycoprotein-mediated drug resistance in CHO cells surviving a single X-ray dose of 30Gy. Int J Radiat Biol, 1993, 63 (6): 765-773.
  • 6Piwnica-Worms D, Chiw ML, Budding M, et al. Functional imaging of mttltidrug resistance P-glycoprotein with an organotechnetium complex. Cancer Res, 1993, 53: 972-984.
  • 7Higashi I, Wakao H, Nakamura K, et al. Quantitative gallium-67 scanning for predictive value in primary lung carcinoma.J Nucl Med, 1980, 21 (7): 628-632.
  • 8Yarnaji S. Usefulness of ^201T1 SPECT in the evaluation of treatment effect for primary lung cancer. Kaku Igaku, 1995, 32(12): 1333-1340.
  • 9Ichiya Y, Kuwabara Y, Sasaki M, et al. A climcal evaluation of FDG-PET to assess the response in radiation therapy for bronchogenic carcinoma. Ann Nucl Med, 1996, 10 (2): 193-200.
  • 10Nishiyama Y, Yamamoto Y, Fukunaga K, et al. Evaluation of radiotherapeutic response in non-small cell lung cancer patients by technetium-99m MIBI and thallium-201 chloride SPECT.Eur J Nucl Med, 2000, 27: 536-541.

共引文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部