摘要
改进Adler法合成了meso-四(对羟基苯基)卟啉(THPP),其结构经UV-Vis,1H NMR和IR表征。合成THPP较适宜的反应条件为:对羟基苯甲醛50 mmol,吡咯50 mmol,丙酸120 mL,DMSO 6 mL,回流反应120min,收率35%。
meso-5,10,15,20-Tetra（4-hydroxylphenyl）porphyrin （THPP） was synthesized by improved Adler＇ s method. The structure was confirmed by UV-Vis, ^1H NMR and IR. The appropriate reaction conditions at reflux for 120 min were as follows： p-hydroxy-benzaldehyde was 50 mmol; pyrrole was 50 mmol; propionic acid was 120 mL; dimethyl sulfoxide was 6 mL. The yield of THPP can reach up to 35% under the reaction conditions.
出处
《合成化学》
CAS
CSCD
2008年第1期86-88,92,共4页
Chinese Journal of Synthetic Chemistry
基金
山西省自然科学基金资助项目(20040402JJ)
关键词
卟啉
合成
工艺改进
porphyrin
synthesis
process improvement
