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阿尔茨海默病小胶质细胞神经毒性研究进展 被引量:1

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摘要 阿尔茨海默病(Alzheimer disease,AD)是一种以进行性认知障碍和记忆力损害为主的中枢神经系统退行性疾病。小胶质细胞(microglia,MG)是中枢神经系统的免疫细胞,在致炎因素作用下小胶质细胞被激活成反应性小胶质细胞,反应性小胶质细胞既具有保护神经元的作用,也能分泌细胞毒因子、补体蛋白而损害神经元。尽管目前其发病机理还不清楚,
作者 蔡志友 晏勇
出处 《中国老年学杂志》 CAS CSCD 北大核心 2008年第4期404-407,共4页 Chinese Journal of Gerontology
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