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鸡抗菌肽Gallinacins生物特性研究进展 被引量：1

Progress on biological characteristics of Gallinacins in chicken
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摘要 在介绍鸡抗菌肽Gallinacins(Gals)组织表达分布的基础上,综述了Gals的基因结构、抗菌作用和主要机制。 Based on a simple introduction to the the tissue expresses and distribution of chicken Gallinacins （Gals）, the article reviewed the relevant gene structure,the antibacterial function and the main mechanism.
作者 李思明 欧阳玲花 周定刚 张恭炜 雷荣苹
机构地区 江西省农业科学院畜牧兽医研究所 四川农业大学动物科技学院
出处 《中国饲料》 北大核心 2008年第3期23-25,共3页 China Feed
基金 江西省农业科学院人才基金项目(2006)
关键词 鸡抗菌肽 Gallinacins 基因表达 抗菌作用 chicken antimicrobial peptides Gallinacins gene expression antibacterial function
分类号 S816.7 [农业科学—饲料科学]
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参考文献13

  • 1Dijk A van,Veldhuizen EJ A,Kalkhove S I C,et al.The β-Defensin Gallinacin-6 Is Expressed in the Chicken Digestive Tract and Has Antimicrobial Activity against Food-Borne Pathogens [J].Antinlicrobial Agents and Chemotherapy ,2007,51 ( 1 ) :912 - 927.
  • 2Harwig S S,Swiderek K M,Kokryakov V N,et al.Ganinacins:cysteine- rich antimicrobial peptides of chicken leukocytes[J].FEBS Lett, 1994,342(3) : 281 - 285.
  • 3Haryadi S,Pak-Lam Y.Mechanisms of action of ostrich β-defensins against Escherichia coli[J].FEMS Microbiology Letters, 2007,270 (2) : 195 - 200.
  • 4Higgs R,Lynn D J,Cahalane S ,et al.Modification of chicken avian beta- defensin-8 at positively selected amino acid sites enhances specific antimicrobial activity[J].Immunogenetics,2007,59(7) :573 - 580.
  • 5Higgs R,Lynn D J,Gaines S,et al.The synthetic form of a novel chicken beta-defensin identified in silico is predominantly active against intestinal pathogens[J].Immunogenetics, 2005,57 ( 1 - 2) : 90 - 98.
  • 6Hiroki O ,Kalpana S .Masahide N ,et al.Expressions of Antimicrobial Peptide Gallinacin-1,-2 and-3 mRNAs in the Oviduct of Laying Hens[J].The Journal of Poultry Science,2005,42(4):337 - 345.
  • 7Lynn D J,Higgs R,Gaines S,et al.Biomformatic discovery and initial characterisation of nine novel antimicrobial peptide genes in the chicken [J]. Immunogenetics, 2004,56 (3) : 170 - 177.
  • 8Milona P,Townes C L,Bevan R M,et al.The chicken host peptides,gallinacins 4,7,and 9 have antimicrobial activity against Salmonella serovars[J]. Biochem Biophys Res Commun,2007,356(1 ) :169 - 174.
  • 9Peschel A.How do bacteria resist human antimicrobial peptides?[J]Trends Microbiol, 2002,10:179 - 186.
  • 10Sadeyen J R., Trotereau J,Velge P,et al.Salmonena carrier state in chicken:comparison of expression of immune response genes between susceptible and resistant animals[J].Microbes Infect, 2004,6 : 1278 - 1286.

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中国饲料
2008年 第3期

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