摘要
目的了解多重耐药的鲍曼不动杆菌(ABA)11簇β-内酰胺酶、3簇金属β-内酰胺酶、4簇OXA类碳青烯酶、2簇AmpC酶、6簇氨基糖苷类修饰酶基因和消毒剂耐药基因携带状况。方法采用PCR检测203株多重耐药的ABA菌耐药基因。结果203株中ADC阳性186株(91.6%)、TEM阳性124株(61.1%)、OXA-23cluster阳性66株(32.5%)、SHV阳性18株(8.9%)、PER阳性6株(3.0%)、DHA阳性1株t(0.5%);ant(3”)-I阳性189株(93.1%)、aac(6’)一Ib阳性118株(58_3%)、aac(3)-I阳性114株(56.2%)、aac(6’)-II阳性13株(6.4%)、ant(2”)-I阳性13株(6.4%)、aac(3)-II阳性10株(4.9%);qacE△1阳性164株(80.8%)。结论多重耐药的ABA菌β-内酰胺酶、OXA类碳青烯酶、AmpC酶、氨基糖苷类修饰酶基因携带率高。
Objective To investigate the drug-resistance and antiseptic-resistance genes in multi-drug resistant A. baumannii (MDR-ABA) strains. Methods The drug-resistance and antiseptic-resistance genes were detected by PCR in 203 strains of (MDR-ABA). Results The positive rates of ADC, TEM, OXA- 23cluster, SHV, PER, DHA, ant (3")- I , aac (6')- I b, aac (3)- I, aac (6')-Ⅱ, ant (2")- I , aac (3)- Ⅱ and qacE△ 1 were 91.6%, 61.1%, 32.5%, 8.9%, 3.0%, 0.5%, 93.1%, 58.3%, 56.2%, 6.4%, 6.4%, 4.9% and 80.8%, respectively. Conclusion There were very high positive percentages of ADC, TEM, OXA-23cluster, ant (3")- I , aac (6')- I b, aac(3)- I and qacE A1 genes in MDR-Al3A.
出处
《世界感染杂志》
2008年第1期15-19,共5页
World Journal of Infection