摘要
目的 观察亚低温疗法对大面积脑梗死患者的临床治疗效果。方法 把92例大面积脑梗死并发高热的患者随机分为亚低温治疗组和对照组各46例。亚低温治疗组给予33～35℃的低温治疗，对照组给予常规物理和药物降温治疗。10d后评定2组患者的体温、心率等指标；1个月后根据死亡率及神经功能缺损评分评估患者的预后。结果 亚低温治疗组患者的体温、心率均低于对照组，死亡率亦低于对照组，神经功能改善（P＜0．05），预后较好。结论 亚低温疗法治疗大面积脑梗死患者安全有效，能够改善患者预后。
Objective To observe the effect of mild hypothermia on patients with massive hemispheric infarction. Methods 92 patients with massive hemispheric infarction and hyperpyrexia were randomly divided into the control group and the hypothermia group with 46 cases in each group, The patients of the hypothermia group were treated with mild hypothermia therapy （33～35 ℃）. Those of the control group were treated with routine hypothermal treatment. The temperature and heart rate of all patients were measured after 10 days, The prognosis was evaluated according to mortality and scores of Neurological Deficit Scale（NDS） after I month. Results In patients of the hypothermia group, the temperature and heart rate significantly reduced, death rate was significantly lower,the neurological function distinctly improved and prognosis was better than the control group after 30 days treatment（ P〈O. 05 ）. Conclusions Mild hypothermia is safe and effective to the patients with massive hemispheric infarction and hyperpyrexia.
出处
《实用全科医学》
2008年第3期266-267,共2页
Applied Journal Of General Practice
关键词
脑梗死
高热
亚低温
预后
Brain infarction
Hyperpyrexia
Hypothermia
Prognosis
