摘要
目的:评估熊去氧胆酸为主结合中医辨证治疗方案对原发性胆汁性肝硬化(PBC)患者实验室指标动态变化的影响。方法:对14例PBC患者从首诊开始每隔6个月的实验室指标(共36个月)的变化进行比较分析。结果:患者AMA/AMA-M2阳性者10例(占71.43%)。与首诊比较,治疗后12个月时的ALT、AST的异常率和均值以及ALP、GGT的异常升高倍数和均值均呈现显著降低(P<0.05);Chol均值于治疗18个月后呈显著降低(P<0.05)。其他指标变化差异无统计学意义。结论:中西医结合治疗可有效延缓PBC病情的进展。
To evaluate the influence of the changing caused by the treatment based on the ursodeoxycholic acid and the integrated traditional Chinese medicine for the patients with primary biliary cirrhosis. Methods： Comparing and analyzing the changing of laboratory indexes for the 14 PBC patients every 6 months from the first time （altogether 36 months） . Results： Between women and men patients the ratio was 13：1, the average age was 52. 64 ＋_ 5.9 and the positive AMA/AMA-M2 patients were 10 （71.43%） . The abnormal rate and average value of ALT and AST, the times in going up extremely and average value of ALP and GGT were declined markedly after the treatment for 12 moths comparing with the first diagnoses （ P 〈 0. 05 respectively） . The average value of Chol was also declined markedly after the treatment for 18 months comparing with the first diagnoses （ P 〈0.05 ） . No significant difference of statistics was in the changing of other indexes. Conclusion： The progression of PBC can be slow down effectively by the integrated traditional Chinese and western medicine.
出处
《中西医结合肝病杂志》
CAS
2008年第1期8-11,共4页
Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
