摘要
收集了我院1994年10月至1995年4月金黄色葡萄球菌100株,应用药敏试验法筛选 MR-SA,并检测其对12种抗生素的耐药性,计算 MIC_(50)和 MIC_(90)。应用乳胶凝集试验法,测定其肠毒素产生率。结果我院总的 MRSA 阳性率为60%,烧伤科的 MRSA 阳性率为67.4%,内科62.5%,骨科44.5%。MRSA 耐药性低于50%的有万古霉素(3.3%)、去甲万古霉素(5%)、丁胺卡那霉素(21.5%)3种。MR-SA 产肠毒素率为100%,其中产两种以上者占35%,而 MSSA 产肠毒素率仅为20%,其中产两种以上者占5%。
100 separate Staphylococcus aureus (S.a) isolates at Beijing Jishuitan Hospital during Oct.1994-Apr.1995 were submitted to determine the proportion of methicillin-resistant S.a (MRSA) and susceptibility test to 12 antibiotics.MIC determinations of the antibiotics were performed.Also,pro- duction rate of enterotoxin was measured with RPLA method.The results showed that MRSA consti- tuted 60% of all cultures.(Burns Dept.67.4%,Internal Medicine 62.5%,Orthopedics Dept.44%).The antibiotics with resistant rate of MRSA below 50% included vancomyin (3.3%),norvancomyin (5%) and amikaciu (21.5%).The production rate of enterotoxin was 100% in MRSA and 20% in MSSA (methicillin-sensitive S.a).In this group,35% of MRSA and 5% of MSSA produced more than 2 types of enterotoxin.
