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2型糖尿病早期应用诺和灵30R人胰岛素治疗临床效果观察

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摘要 目的:探讨2型糖尿病早期应用胰岛素治疗对胰岛素抵抗和代谢紊乱的影响。方法t将50例初诊2型糖尿病患者随机分为2组,在基础治疗的前提下,笔者分别采用诺和笔3,每日2次皮下注射预混型诺和灵30R人胰岛素(30%速效胰岛素与70%中效胰岛素预先混和制剂,最大作用时间2~8h,维持作用时间可达24h,简称预混人胰岛素,hIns)治疗和口服降糖药治疗30d,治疗前后观察空腹和餐后2h血糖、糖化血清蛋白,血胆固醇、甘油三酯的变化。结果:应用诺和灵30R人胰岛素治疗组空腹和餐后2h血糖、糖化血清蛋白,血胆固醇、甘油三酯均较对照组有明显的下降,P〈0.05。结论:诺和灵30R人胰岛素治疗糖尿病对降低空腹、餐后血糖及糖化血清蛋白具有作用明显,安全性、耐受性良好的特点且能更好地纠正血脂代谢紊乱。
作者 王淑萍
出处 《医学理论与实践》 2008年第3期299-300,共2页 The Journal of Medical Theory and Practice
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