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天疱疮的诊断及治疗研究进展 被引量:12

Advances on Diagnosis and Therapeutics of Pemphigus Vulgaris and Pemphigus Foliaceus
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摘要 疱疮是自身免疫性疾病,患者体内产生的抗桥粒芯糖蛋白抗体与抗原结合,致细胞间黏附性丧失、棘层松解。直接免疫荧光法诊断可靠,患者头发外毛根鞘也可显示阳性结果。间接免疫荧光法观察循环中自身抗体,可了解病情变化和治疗效果;酶联免疫吸附试验也可检测循环抗体,可对抗体进行分型,敏感性高。治疗天疱疮首选糖皮质激素,但副作用较大。环孢素、霉酚酸酯、利妥昔单抗、免疫球蛋白冲击、免疫吸附疗法等辅助药物、疗法也有更深入研究。
出处 《中国皮肤性病学杂志》 CAS 北大核心 2008年第2期115-117,共3页 The Chinese Journal of Dermatovenereology
关键词 天疱疮 诊断 治疗
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参考文献19

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